Rupatadine Impurity 35 dihydrate CAS 1632412-57-7(Anhydrous CAS)
| CAS No. | 1632412-57-7(Anhydrous CAS) |
| Molecular Formula | C29H30ClN3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Rupatadine Impurity 35 dihydrate (C29H30ClN3O2H2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Rupatadine Impurity 35 dihydrate (CAS 1632412-57-7(Anhydrous CAS)), a pharmacopoeial impurity reference standard (molecular formula C29H30ClN3O2H2O, MW 506.04 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rupatadine Impurity 35 dihydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H30ClN3O2 2*H2O |
| Molecular Weight | 506.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rupatadine Standards
- Rupatadine Impurity 21 (CAS 1007089-84-0)
- Rupatadine Impurity 24 (CAS 100910-66-5)
- Rupatadine Impurity 3 (CAS 102074-19-1)
- Rupatadine impurity 1 (CAS 1118754-56-5)
- Rupatadine impurity 14 (CAS 1210824-61-5)
- Rupatadine EP Impurity C (CAS 1224515-72-3)
- Rupatadine Impurity 4 (CAS 1235342-53-6)
- Rupatadine EP Impurity A (CAS 1354055-68-7)
Recommended Standards
- Voriconazole Impurity 53 (CAS 759-67-1)
- Hydrochlorothiazide impurity 48 (CAS CATO-C4X-117748)
- Choline impurity 4 (CAS CATO-C4X-15874)
- 2-Fluoro-5-methoxy-3-methylpyridine (CAS 1228898-05-2)
- 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS 71193-32-3)
- 4,5-Difluoro-2-formylbenzonitrile (CAS 1807177-35-0)
- 2-(Acetylamino)-2-[2-(4-bromo-2-chlorophenyl)ethyl]propanedioic Acid 1,3-Diethyl Ester (CAS 1346604-54-3)
- 6,7-Dimethyl-2,3-dihydro-1-benzofuran-3-amine hydrochloride (CAS 1258649-70-5)
- (2,2-Dimethyl-1-phenylcyclopropyl)methanamine (CAS 884091-19-4)
- [Ser39-OH] Tirzepatide (CAS CATO-C4X-324041)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com